Spastic paraplegia four (SPG4; often known as SPAST-HSP) is characterised by insidiously progressive bilateral reduce-limb gait spasticity. Greater than 50% of affected people have some weakness inside the legs and impaired vibration sense on the ankles.?? ????? ???? ??? ???? ?? ??? ? ?? ???? ??? ? ????. ?? ????? ??? ????? ??? ???? ?? ???? ??????!?